منابع مشابه
NEJM -- Toxic Leukoencephalopathy
PubMed Citation Leukoencephalopathy is a structural alteration of cerebral white matter in which myelin suffers the most damage. Toxic leukoencephalopathy may be caused by exposure to a wide variety of agents, including cranial irradiation, therapeutic agents, drugs of abuse, and environmental toxins.1 Toxic leukoencephalopathy particularly involves white-matter tracts devoted to higher cerebra...
متن کاملToxic leukoencephalopathy after inhalation of poisoned heroin: MR findings.
Retrospective MR studies of four patients with neurologic symptoms after inhalation of contaminated heroin vapor revealed extensive, typically symmetrical lesions in the white matter of the cerebrum, cerebellum, and midbrain. Selective involvement of the corticospinal tract, the solitary tract, and the lemniscus medialis also has been found.
متن کاملToxic Leukoencephalopathy and Hypokalemia Due to Exposure to Trimethyltin
Dear Editor, Trimethyltin (TMT) is a by-product of organotin compounds, which are widely used as heat stabilizers. Unfortunately, TMT is a toxicant affecting several organs, including the brain.1 Herein we describe a case of TMT intoxication characterized by symmetrical leukoencephalopathy and severe hypokalemia. A previously healthy 22-year-old man presented with subacute headache, amnesia, an...
متن کاملToxic Leukoencephalopathy and Delayed Neuropsychosis after Opioid Overdose
First time neuro-psychiatric disorders in the emergency department present a challenging and broad differential. Physicians often anchor on recent substance abuse as a possible cause of acute mental status change. Overlooked, however, is the occurrence of delayed sequelae as a result of a severe intoxication. This article describes the occurrence of neurologic injury at a delayed interval follo...
متن کامل5-Fluorouracil (5-FU) Induced Acute Toxic Leukoencephalopathy
This is a 57-year-old right-handed male with a history of locally advanced esophageal adenocarcinoma, who presented with confusion and speech changes. Patient received 5-Fluorouracil (5-FU) and cisplatin four days prior to presentation, which was complicated by very poor oral intake on day 2 of therapy. On the day of presentation, he was confused and his speech was slurred. The remainder of the...
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ژورنال
عنوان ژورنال: MOJ Toxicology
سال: 2016
ISSN: 2379-6294
DOI: 10.15406/mojt.2016.02.00033